STK11/LKB1 Peutz-Jeghers Gene Inactivation in Intraductal Papillary-Mucinous Neoplasms of the Pancreas
نویسندگان
چکیده
منابع مشابه
Intraductal papillary mucinous neoplasms of the pancreas.
BACKGROUND/AIMS Intraductal papillary mucinous neoplasms (IPMNs) are neoplasms of the pancreatic duct epithelium characterized by intraductal papillary growth and thick mucin secretion. Quantities of mucin fill the main and/or branches of pancreatic ducts and cause ductal dilatation. This review encompasses IPMNs, including symptoms, diagnosis, management, and prognosis. METHODS A Pubmed data...
متن کاملManagement of intraductal papillary mucinous neoplasms of the pancreas.
Over the last decade, the diagnosis and treatment of intraductal papillary mucinous tumors (IPMN) of the pancreas has evolved. They represent a spectrum of disease, ranging from benign to malignant lesions, making the early detection and characterization of these lesions important. Several non-invasive and invasive imaging modalities allow adequate visualization of these lesions. Multidetec-tor...
متن کاملIntraductal Papillary Mucinous Neoplasms of Pancreas- A Review
Intraductal papillary mucinous neoplasms of pancreas are relatively common, often arise from the pancreatic head, and comprise more than one third of resected pancreatic cysts. In these lesions, the risk of dysplasia or carcinoma varies according to the site of ductal involvement or histologic subtypes. For instance, there is a higher risk of malignancy associated with main rather than branch d...
متن کاملIntraductal papillary mucinous tumors of the pancreas
Intraductal papillary mucinous tumors (IPMTs) are benign and malignant lesions that arise from the epithelial lining of main pancreatic duct and/or branch pancreatic ducts, with excessive mucin production (especially hyperplastic/adenomatous variety). Based on the degree of cytoarchitectural atypia on microscopic examination, IPMTs are classified as benign, borderline, carcinoma in situ and inv...
متن کاملIntraductal Papillary Mucinous Neoplasms: The Bologna Experience
Background In the last decades, the attention to Intraductal Papillary Mucinous Neoplasms (IPMNs) has risen due to the increase of their incidental diagnosis. The aim of the present study was to evaluate which factors influenced survival in population affected by intraductal papillary mucinous neoplasms. Methods A retrospective study on a prospective database of 357 patients observed at our Ins...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2001
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)63053-2